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|Authors:||Крюкова, Н. А.|
Глазычев, Ю. И.
Слепнева, И. А.
Черткова, Е. А.
Глупов, В. В.
|Title:||Влияние яда Habrobracon hebetor на клеточный иммунитет пчелиной огневки Galleria mellonella|
|Other Titles:||The influence on the cell immunity of the great wax moth Galleria mellonella by the Habrobracon hebetor venom|
|Description:||Ectoparasitoids inject venom into hemolymph during oviposition. We determined the influence of envenomation by the parasitoid, Habrobracon hebetor, on the hemocytes of its larval host, Galleria mellonella. It was detected that the parasitoids actively suppress prophenoloxidase complex in haemocytes. At the same time the quantity of the haemocytes generating free radical oxygen species was increased. The encapsulation rate of infected larvae during parasitoid development was the same as the control. An increase in both intracellular Ca2+ content and phospholipase C activity of the host hemocytes was recorded during 2 days following envenomation by the parasitoid. The decreased hemocyte viability was detected 1, 2, and 24 h after the envenomation. Injecting of the crude venom (final protein concentration 3 μg/ml) into the G. mellonella larvae led to the reduced hemocyte adhesion. The larval envenomation caused a decrease in transmembrane potential of the hemocytes. These findings document the suppression of hemocytic immune effectors in the parasitized host larvae.|
|Appears in Collections:||Современные проблемы теоретической и морской паразитологии / Contemporary problems of theoretical and marine parasitology|
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